The Sun reports that up to 10,000 are feared dead, with many including children trapped in the rubble, after two high-magnitude shocks.
All money raised will be donated to the British Red Cross for a major on-the-ground mobilisation, says the publisher.
Red Crescent staff are already distributing essentials such as food, water, blankets and temporary shelters to support survivors who spent the night outside in freezing temperatures.
Support is also being provided for traumatised people.
To donate, visit redcross.org.uk/sunaid.
British Red Cross chief executive Mike Adamson said: “The scale of destruction caused by these earthquakes has been devastating.
“The priority right now is rescuing people from the rubble.
“Your donations will help search-and-rescue missions on the ground — and provide vital aid to those who need it most.
“We thank Sun readers for your kind support.
“Anything you give makes a difference.”
Text THESUN to 70141 to make a £5 donation to the Sun Earthquake Appeal.
Texts cost £5 or your chosen donation amount +1 standard message (we receive 100%).
For full T&Cs visit redcross.org.uk/mobile.
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